Genotoxicity assessments

Citterio S, Aina R, Labra M, Ghiani A, Fumagalli P, Sgorbati S, Santagostino A. 2002. Soil genotoxicity assessment a new strategy based on biomolecular tools and plant bio-indicators. Environ Sci Technol 36 2748-2753. [Pg.171]

Computational Approaches to Genotoxicity Assessment In Silica Assessment... [Pg.250]

A theme throughout this chapter is the difference between genotoxicity assessment in hazard profiling and safety assessment applications. This comes more acutely into focus in this section where the follow-up to positive profiling tests is considered. The default expectation is that the follow-up for a positive early profiling test would be removal of the compound from the collection going forward the aim of a screening... [Pg.260]

Hastwell, P.W., Chai, L.-L., Roberts, K.J., Webster, T.W., Harvey, J.S., Rees, R.W. and Walmsley, R.M. (2006) High-specificity and high-sensitivity genotoxicity assessment in a human cell line Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay. Mutation Research, 607, 160-175. [Pg.268]

Muller, L., and Kasper, P. (2000). Human biological relevance and the use of threshold-arguments in regulatory genotoxicity assessment Experience with pharmaceuticals. Mutat Res 464, 19-34. [Pg.353]

Citterio S et al., Soil genotoxicity assessment A new strategy based on biomolecular tools and plant bioindicators, Environ. Sci. Technol., 36, 2748, 2002. [Pg.208]

Rivera, I.G., M.T. Martins, PS. Sanchez, et al. 1994. Genotoxicity assessment through the Ames test of medicinal plants commonly used in Brazil. Env. Toxicol. Water Qual. 9(2) 87-93. [Pg.128]

Pfculo F, Guiraldeli Macedo C, de Andrade SF, Luis Maistro E (2011) In vivo genotoxicity assessment of nerolidol. J Appl Toxicol 31(7) 633-639... [Pg.4153]

Genotoxic assessment in different exposure groups working with antineoplastic agents... [Pg.177]

In what concern to genotoxicity assessment, the results showed statistical significant higher means for some endpoints studied between the three professions groups and controls (p < 0.05). These results, namely in what concern to micronuclei frequency, are corroborated by many others studies (Kopjar et al., 2009 El-Ebiary et al., 2011) that found also significant increase of micronuclei frequency in workers handling antineoplastic drugs. [Pg.180]

Sachs G, Scott D (1990) Cell digestion and genotoxicity assessment in gastric mucosa. Digestion 47 (Suppl 1) 31-34... [Pg.142]

Wagner, S. J. Cifone, M. A. Murli, H. Dodd, R. Y Myhr, B. Jerome, H. Mammalian genotoxicity assessment of methylene blue in plasma implications for virus inactivation. Transfusion 1995, 35, 407-413. [Pg.294]

R. Zounkova, L. Kovalova, L. Blaha and W. Dott, Ecotoxicity and genotoxicity assessment of cytotoxic antineoplastic drugs and their metabolites, Chemosphere, 2010, 81, 253-260. [Pg.405]

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