Genome database overview

An overview of databases yields the number of publicly accessible genomes 112 finished microbial and two eukaryotic genomes with over 300 overall in progress (as of April 2003). The number of enzymes with E.C. nomenclature is 4159 according to the ExPASy website and 3225 according to Brenda databases the number of accessible 3D structures totals 20 946, 18 872 of which are proteins. 

Mewes HW, Albermann K, Bahr M, Frishman D, Gleissner A, Hani J, Heuman K, Kleine K, Maierl A, Oliver SG, Pfeifer F, Zollner A Overview of the yeast genome. Nature 1997 387 7-65. Mewes HW, Albermann K, Heumann K, Liebl S, Pfeifer F MIPS A database for protein sequences, homology data and yeast genome information. Nucleic Acid Res 1997 35 28-30. Clarke L, Baum MP Functional analysis of a centromere from fission yeast A role for centromere-specific repeated DNA sequences. Mol Cell Biol 1990 10 1863-1872. 

The IntegrS portal (http //ebi.ac.uk/integr8) offers an overview of information about organism with completely sequenced genomes, statistical analysis of their genomes/ proteomes individually and comparatively. The database is build on three main sources (Kersey et al, 2005) ... 

Lesk, Arthur M. Introduction to Bioinformatics. 3d ed. New York Oxford University Press, 2008. Comprehensive overview of genomes, proteomics, protein structure, databases, phylogenetics, programming languages, and more. 

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