GENETIC TOXICOLOGY TESTING GUIDELINES AND REGULATIONS

Cancer Risk Assessment, edited by Ching-Hung Hsu and Todd Stedeford Copyright 2010 John Wiley Sons, Inc. 

Guidelines for testing environmental chemicals in the United States were delineated during the 1970s and 1980s (Auletta et al. 1993 Waters and Auletta 1981) and for food additives in 1982 (FDA 1982). Classically, the first batteries included (1) a bacterial test for gene mutation, (2) either an in vitro test for chromosomal 

A similar evaluation addressing the experience in Germany with the review of tests for 776 new chemicals reviewed between 1982 and 1997 has been published 

CHAPTER 10 GENETIC TOXICOEOGY TESTING GUIDEEINES AND REGULATIONS 

The Organisation for Economic Cooperation and Development (OECD) test guidelines 

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GENETIC TOXICOLOGY, TESTING GUIDELINES AND REGULATIONS, AND NOVEL ASSAYS... 

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