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Genetic mosaic

Lakahashi Everyone is working on tissue-specific knockouts and inducible expression. But no one is there yet. The hardest part is getting SCN drivers the liver and the periphery are already done. Not much work has been done with genetic mosaics. The problem with mosaics in mice is that they are very fine grained. You can get patches, but you have to do cross-species work. [Pg.72]

W. Janning, Gynandromorph fate maps in Drosophila. In Genetic Mosaics and Cell Differentiation, W. J. Gehring, ed., Springer-Verlag, Berlin, 1978, pp. 1-28. [Pg.243]

Frank SA (2010) Evolution in health and medicine Sackler colloquium somatic evolutionary genomics mutations during development cause highly variable genetic mosaicism with risk of cancer and neurodegeneration. Proc Natl Acad Sci U S A 107(Suppl 1) 1725-1730... [Pg.326]

Mintz, B., and Illmensee, K. (1975). Normal genetically mosaic mice produced from malignant terato-carcinoma cells. Proc Natl Acad Sci USA 72(9), 3585-3589. [Pg.162]

All cases of mosaicism can be divided into two large groups if the classification of Russell (1964) is slightly modified (1) structural-genetical mosaicism where the... [Pg.162]

The best known case of structural-genetical mosaicism is the Lyonization which was discussed in Chap. 1.3.3.2. This phenomenon is characterized by the formation of cell clones which differ in X chromosome activities. [Pg.169]

The analysis of compartmentalization in Drosophila has most commonly been done in genetic mosaics which resulted from the induction of somatic crossing-over. The Minute mutation has been useful in such experiments. The cell... [Pg.181]

Stem C (1968) Genetic mosaics and other essays. Harvard Univ Press, Cambridge... [Pg.304]

Xu T. and Rubin G.M. 1993. Anal) is of genetic mosaics in developing and adult Drosophila tissues. Development 117 1223—1237. [Pg.173]

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See also in sourсe #XX -- [ Pg.81 , Pg.82 , Pg.83 , Pg.84 , Pg.85 , Pg.86 , Pg.87 , Pg.88 , Pg.89 , Pg.90 ]



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