Genetic engineering strategy

Schoffi, F. (1988). Genetic engineering strategies for manipulation of the heat shock response. Plant, Cell and Environment 11, 339-43. 

Acetylcholinesterase inhibition has been widely used for pesticide detection [88-94], but less exploited than protein phosphatase inhibition for cyanobacterial toxin detection. Nevertheless, the anatoxin-a(s) has more inhibition power than most insecticides, as demonstrated by the higher inhibition rates [95]. In order to detect toxin concentrations smaller than usually, mutant enzymes with increased sensitivity were obtained by genetic engineering strategies residue replacement, deletion, insertion and combination of mutations. Modifications close to the active site, located at the bottom of a narrow gorge, made the entrance of the toxin easier and enhanced the sensitivity of the enzyme. 

Fulekar, M.H., Singh, A., and Bhaduri, A.M. 2009. Genetic engineering strategies for enhancing phytoremediation of heavy metals. African Journal of Biotechnology, 8(4) 529-35. 

For more than 20 years, various industrial, governmental, and academic laboratories have developed and refined genetic engineering strategies aimed at manipulating lipid metabolism in plants and microbes. The goal of these projects is to produce... 

Tang W (2003) Recent advances in the molecular genetics of resin biosynthesis and genetic engineering strategies to improve defenses in conifers. J Forest Res 14 171-179... 

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