Gene transfection, cationic cylindrical

The unique stmcture of cylindrical bmshes makes them ideal candidates to (1) experimentally and theoretically study the phase separation in quasi -ID molecular objects, (2) investigate the properties of polyelectrolyte complexes of shape-persistent polyions, (3) elucidate the adsorption on planar surfaces, and eventually (4) develop novel cationic carriers for gene transfection, as described in detail in Sect. 4. [Pg.165]

Gene Transfection Utilizing Cationic Cylindrical Brush Polymers. 225... [Pg.212]

As described above, cationically modified albumin was successfully utilized in gene transfection experiments. A novel cylindrical structure of poly-L-lysine (PEL) in the form of a cylindrical brush polymer with PEL side chains has been utilized for DNA transfectimi. The results are compared with the transfection efficiency of flexible linear PEE/DNA complexes. [Pg.225]

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