Gene structure, determination

The two subsidiaries consider here are deCODE Biostructures and deCODE Chemistry. deCODE Biostructures provides solutions to its clients in gene synthesis, determination of three-dimensional protein-ligand structures, and pre-formulation screening... 

Matias, P. M., Soares, C. M., Saraiva, L. M., Coelho, R., Morais, J., LeGall, J. and Carrondo, M. A. (2001) [NiFe] hydrogenase from Desulfovibrio desulfuricans ATCC 27774 gene sequencing, three-dimensional structure determination and refinement at 1.8 angstrom and... 

Two different isoforms, COX-1 and COX-2, encoded by two genes have been cloned and sequenced (Table 1 Funk et al., 1991 Kujubu et al., 1991 Hla and Neilson, 1992 O Banion et al., 1992). The cloning of the two isoforms led to further characterization of the enzymes by means of a whole range of molecular biology tools from experiments using knock-out mice (Dinchuk et al., 1995 Langenbach et al., 1995 Morham et al., 1995) to protein structure determination (Picot et al., 1994 Kiefer et al., 2000). 

Estrogen receptor gene (ESR1) genomic structure determined 15... 

Vitamin D receptor gene genomic structure determined 43... 

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