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Gene identification programs

Promoters. The promoter is an information-rich signal that regulates transcription, especially for eukaryotes. Computer recognition of promoters (Fickett and Hatzigeorgiou, 1997) is important partly for the advance it may provide in gene identification. Available programs include those depending primarily on simple... [Pg.187]

Figure 10.11. Outputs from FGENESH and FGENE of GeneFinder. The nucleotide sequence of DNA encoding human lysozyme (5648 bp) is submitted to Sanger Centre for gene identification with FGenesh (hidden Markov model) and Fgene (pattern recognition) tools. The identical translate is predicted by the two programs. Figure 10.11. Outputs from FGENESH and FGENE of GeneFinder. The nucleotide sequence of DNA encoding human lysozyme (5648 bp) is submitted to Sanger Centre for gene identification with FGenesh (hidden Markov model) and Fgene (pattern recognition) tools. The identical translate is predicted by the two programs.
More recently, many integrated programs for gene structure prediction and gene identification have been developed. Several of them, including GRAIL (Uberbacher et... [Pg.105]

Gene identification, and finding of ORFs, promoters and splice sites by the methods described above is available via World Wide Web. Table 3.19 presents a list of some useful programs but does not provide a comprehensive collection. [Pg.122]

It begins to become evident that no one program provides the foolproof key to computational gene identification. The correct choice will depend on the nature of... [Pg.248]


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Genes identification

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