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Gastrointestinal drug absorption membrane factors

The small intestine is the most important organ for drug absorption in the gastrointestinal tract. The surface area of the intestine is approximately 200 m (Caspary, 1992) because of the presence of well-developed vilh. Collapsibility, drug solubility, and membrane permeability are the most influential factors in determining Fa- Solubility in aqueous solution is a critical factor in optimizing Fa (Ku, 2008). [Pg.207]

The surface area available for absorption in the buccal mucosa is much smaller than the gastrointestinal, nasal, rectal, and vaginal mucosae. The buccal mucosa is continuously bathed by saliva, and the secreted saliva lowers the drug concentration at the absorbing membrane. These two factors, along with the permeability... [Pg.2664]

See other pages where Gastrointestinal drug absorption membrane factors is mentioned: [Pg.421]    [Pg.431]    [Pg.36]    [Pg.666]    [Pg.421]    [Pg.46]    [Pg.113]    [Pg.113]    [Pg.249]    [Pg.156]    [Pg.25]    [Pg.46]    [Pg.2631]    [Pg.658]    [Pg.10]    [Pg.16]    [Pg.90]    [Pg.353]    [Pg.459]    [Pg.462]    [Pg.249]    [Pg.30]    [Pg.6]    [Pg.421]    [Pg.523]    [Pg.39]    [Pg.161]    [Pg.144]    [Pg.359]    [Pg.100]    [Pg.296]    [Pg.62]    [Pg.141]    [Pg.90]    [Pg.77]    [Pg.26]    [Pg.96]    [Pg.248]    [Pg.72]   
See also in sourсe #XX -- [ Pg.211 , Pg.211 , Pg.212 , Pg.212 , Pg.213 ]



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Absorption membrane

Drug absorption

Drug-membrane

Gastrointestinal absorption

Gastrointestinal drug absorption

Gastrointestinal drugs

Gastrointestinal factors

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