Gastric juice universal

About 1895 Benjamin Moore, then an assistant professor of physiological chemistry at University College London, began to assemble data for his chapter on Chemistry of the Digestive Processes, to be published in 1898 in the first volume of E. A. Schafer s Text-book of Physiology To establish the composition of gastric juice, Moore quoted the data that Carl Schmidt had collected in Dorpat and had published in Bidder and Schmidt s Die Verdauungssaefte und der Stoffwechsel in 1852 (Table 1-1). ... 

Figure 1-7. A "Gamblegram" showing the relationship between the electrolyte composition of cats gastric juice and blood plasma. (From Gamble JA, Mclver MA. The acid-base composition of gastric secretions. I Exp Med 48 837-857, 1928, by copyright permission of the Rockefeller University Press.)...

In complete ignorance of Lipschitz s work, I undertook a study of gastric secretion of iodide in 1939-40 when I was at the University of Rochester, and I continued it when I moved to Yale. I gave sodium iodide intravenously and collected simultaneous samples of pouch gastric juice and of venous blood. I measured total... 

As equation (1-5) predicts, the ratio in gastric juice should reach very high values when tracer amounts are used. In early studies reported in 1947, values of 20 to 40 were obtained, and in 1950 N. B. Myant and his colleagues at University College Hospital in London obtained values averaging 40 in three patients. ... 

Methods for preparation and analysis of macromolecules improved in the late 1960s, and in 1973 Robert Allen and Carol Mehlman of Washington University in St. Louis reported the isolation of a homogeneous mucoprotein from Histalog-stimulated human gastric juice that was effective in promoting vitamin B12 absorption in one patient in a dose of 2 ixg. Allen and Mehlman used affinity chromatography, in which the intrinsic factor in solution attaches itself to vitamin B12 anchored on Sepharose, as their sole means of isolation. The molecule contained... 

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