G-protein signaling pathways

Ross, E. M. Palmitoylation in G protein signaling pathways. Curr. Biol. 5 107-109,1995. 

Lichtarge, O., Sowa, M. E., and Philippi, A. (2002) Evolutionary traces of functional surfaces along G protein signaling pathway. Methods Enzymol. 344, 536-556. 

Fig. 2 Yeast-based functional screen for receptor-independent activators of G-protein signaling. The yeast strain indicated in A was generated as described previously (Cismowski et al. 1999, 2002) and transformed with mammalian cDNA libraries in the galactose-inducible yeast expression vector pYES2. The strategy for identifying mammalian cDNAs that promoted growth (i.e., activated G-protein signaling pathway) is indicated in B. GALlp GALl promoter)...

Takesono A, Cismowski Ml, Ribas C, Bernard M, Chung P, Hazard 111 S, Duzic E, Lanier SM (1999) Receptor-independent activators of heterotrimeric G-protein signaling pathways. J Biol Chem 274 33202-33205... 

Teriparatide These hormones act on their cognate receptors coupled to G protein signaling pathways Teriparatide stimulates bone turnover, calcitonin suppresses bone resorption Both are used in osteoporosis calcitonin is used for hypercalcemia Teriparatide may cause hypercalcemia and hypercalciuria... 

Ross, E.M. (1992b). Twists and turns on G-protein signalling pathways. Curr. Biol. 2, 517 519. 

Activation of G-protein-coupled receptors. There are many routes by which ligandbinding to G-protein-coupled receptors can transmit signals to the ERK pathway (review Liebmann, 2001), and activation of the ERK pathway is frequently observed upon ligand binding to G-protein-coupled receptors. A main entry point is the Raf kinase, which can be activated by protein kinase C and inhibited by protein kinase A. As outlined in Sections 7.3 and 7.4, both enzyme families can be activated via G-protein-signaling pathways by multiple mechanisms. 

SHIMIZU, K., KELLER, N.P., Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions m Aspergillus nidulans. Genetics, 2001,157, 591-600. 

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