Further Functionalization of Nanodiamond

A modification of functional groups already attached to the nanodiamond surface is of considerable interest for the development of new diamond materials for biomedical or mechanical applications. 

Other reactions on chlorinated nanodiamonds include radical reactions with cresols and related alkylaromatic compounds. p-Cresol, for instance, allows for the introduction of terminal phenolic groups that may serve as valuable starting-point for the incorporation into polymers (Section 5.5.2.9) or for the attachment of biologically active moieties. 

There is, however, a certain drawback to nanodiamonds modified by esterification or amidation at a variety of conditions, these groups are cleft again (e.g., by ester saponification), so derivatized nanodiamonds of this kind can only be employed in comparatively gentle environments. 

the hydroxyl groups may serve to attach trialkoxy silanes. 

The formation of O-acyl groups on the surface can also be realized starting from hydrogenated diamond. To this purpose, it is initiaUy treated with a diacyl peroxide like dibenzoyl or dUauroyl peroxide. The reagent is thermally cleft to give two radicals that can generate radical centers on the diamond surface by hydrogen abstraction. These positions may then be reacted with a variety of 

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