Fundamental Aspects of Salts and Co-crystals

Department of Physics and Chemistry, University of Southern Denmark, 

Tn the academic literature, the solid-component definition of a co-crystal is frequently accompanied by a reference to a 2005 review paper by Aakeroy and Salmon. This is unfair, since these authors state very clearly in thdr paper that it is not their intention to apply any such definition. Specifically, they write The purpose of this artiele is not to propose new definitions or to weigh in on the current semantic/semiotic debate, but it will be necessary to delineate the scientific realm of this [review] . One criterion applied to limit the realm of the review is that Only co-crystals made from reactants that are solids at ambient eonditions will be included , with an accompanying footnote that states One could also make a ease for including materials such as those prepared through co-condensation (of liquids or gases) at reduced temperatures or elevated pressure . 

3 Supramolecular Chemistry, Intermolecular Interactions and Crystal Packing 

The close relationship between crystal engineering and supramolecular chemistry is often expressed by the quote that a crystal is a supermolecule par 

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