Functionalization poly dendrons

Huang, B., and Tomalia, D.A. (2005) Dendronization of gold and CdSe/cdS (core-shell) quantum dots with tomalia type, thiol core, functionalized poly(amidoamine) (PAMAM) dendrons. J. Lumin. Ill, 215-223. 

Pitto-Barry A, Barry NPE, Zava O, Deschenaux R, Dyson PJ, Therrien B (2011) Encapsulation of pyrene-functionalized poly(benzyl ether) dendrons into a water-soluble organometallic cage. Chem Asian J 6 1595-1603... 

Dendrimers have been used as large compartmented hosts for drug delivery, as carriers for catalytically active sites in flow reactors, and for charge or energy transfer purposes. New types of such dendrimers were prepared starting from functionalized poly-p-phcnylcncs as polymeric cores whose functional groups were further used to anchor dendrons [165]. The polymers were synthesized from dibromide 117 and diboronic acid 118 via a Suzuki crosscoupling the dendrons were attached via a Williamson ether synthesis [165]. 

One of the most comprehensive examinations of dendritic nanoscale amphiphiles involved structures that mimicked traditional surfactants. This work was reported in a thesis by van Hest et al. [126] [166]. In this study, extensive hydrophobic tails were precisely constructed by the living anionic polymerization of styrene, followed by termination with a primary amine function. Dendronization of these amine functionalized poly(styrenes) produced focal point functionalized, hydrophobically substituted PPI dendrons, as illustrated later (Figure 23). More specifically, the living polystyrene anion is terminated with ethyleneoxide, thus providing a hydroxyl terminated poly(styrene) with... 

Figure23 Linear-poly(styrene), focal point functionalized poly(propyleneimine) (PPI) dendrons G = 4.0.

Some of fhe earliesf work was reported by Frechet et al. in 1993 [253]. It involved the examination of LB films derived from the spreading of amphiphilic hydroxyl functionalized poly(arylether) dendrons as a function of generation level (i.e., G = 1-5) (Figure 36). 

The relatively mild synthetic conditions during iterative growth of poly(benzyl ether) dendrons are tolerated by many peripheral groups (e.g. cyano, bromide functionality, alkyl ester, alkyl ether, perfluoroalkyl ether, oligo(ethylene glycol)... 

With the previously demonstrated ability of trinuclear gold(I) pyrazo-late complexes that possess long-alkyl chains to form columnar mesophases [119-121], Aida and co-workers synthesized a series of luminescent Au3 complexes bearing dendritic poly(benzyl ether) functionalized pyrazole ligands [122]. By controlling the dendron generation, superhelical fibres with extensive inter molecular Au3 stacking could be obtained, which resulted in an... 

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