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Functional targets carbohydrates

Many extracellular proteins are glycoconjugates, containing covalently bound polysaccharides that contribute to stability of the protein and may have a signaling function in cellular targeting. Carbohydrate residues are attached to proteins during secretion from the cell by specialized glycosyl transferases localized in the secretory pathway... [Pg.5498]

As illustrated above, utilization of the targeting function of carbohydrates has enabled efficient enzyme replacement therapy and its clinical application. Efforts are currently being made to develop new technology to ensure adequate amounts of enzymes and to enable the application of this kind of drug to the treatment of lysosome disease complicated by disorders of the central nervous system. [Pg.2387]

See other pages where Functional targets carbohydrates is mentioned: [Pg.171]    [Pg.2380]    [Pg.2380]    [Pg.428]    [Pg.699]    [Pg.126]    [Pg.135]    [Pg.147]    [Pg.240]    [Pg.13]    [Pg.269]    [Pg.461]    [Pg.136]    [Pg.257]    [Pg.337]    [Pg.170]    [Pg.178]    [Pg.189]    [Pg.253]    [Pg.287]    [Pg.289]    [Pg.5]    [Pg.3]    [Pg.3]    [Pg.20]    [Pg.22]    [Pg.40]    [Pg.43]    [Pg.49]    [Pg.139]    [Pg.213]    [Pg.300]    [Pg.367]    [Pg.526]    [Pg.671]    [Pg.684]    [Pg.787]    [Pg.822]    [Pg.900]    [Pg.1229]    [Pg.164]    [Pg.35]    [Pg.85]    [Pg.163]    [Pg.272]    [Pg.247]    [Pg.641]    [Pg.48]   
See also in sourсe #XX -- [ Pg.35 ]



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