Frontal affinity chromatography-mass

Frontal Affinity Chromatography - Mass Spectrometry for Ligand Discovery and Characterization... [Pg.217]

P. J., Kelly, M. A., Schriemer, D. C. Frontal affinity chromatography-mass spectrometry assay technology for multiple stages of drug discovery applications of a chromatographic... [Pg.244]

K. Kelly, M. Frontal Affinity Chromatography Mass Spectrometry (FAC-MS) Method Evaluation with a Nuclear Hormone Receptor, in Proceedings of the 49th ASMS Conference on Mass Spectrometry and Allied Topics, Long Beach, CA, June 11-15, 2000, TPF 228. [Pg.60]

Automated multiple ligand screening by frontal affinity chromatography-mass spectrometry (FAC-MS). J. Biomol. Screen., 12, 167-174. [Pg.36]

Frontal affinity chromatography-mass spectrometry (FAC-MS) is very popular for ligand and inhibitor discovery and design [36], This two-dimensional detection method physically separates compounds by affinity chromatography and determines their identities by MS. Introduced in 1999 [37], FAC-MS is capable of ranking several compounds present in solution in terms of their binding... [Pg.132]

Ng,W., Dai, J. R., Slon-Usakiewicz, J. J, Redden, P. R., Pasternak, A., Reid, N. (2007). Automated multiple ligand screening by frontal affinity chromatography-mass spectrometry (FAC-MS). J. BiomoL Screen., 12, 167-174. [Pg.145]

Chan, R, Lewis, D., Kelly, M., Ng, E.S.M., and Schriemer, D.C (2007) Frontal Affinity Chromatography Mass Spectrometry for Ligand Discovery and Characterization, in Mass Spectrometry in Medicinal Chemistry Applications in Drug Discovery (eds K. T. Wanner and G. Hofher), Wiley-VCH Verlag GmbH ... [Pg.423]