Frequency of tests

Depending on the location of the workplace, the regulations will indicate the frequency of tests and examination of the equipment. 

Also, the particular boiler plant water-steam chemistries must be reviewed and interpreted at regular intervals. The specifics and complexity of this work depend on the type of boiler plant involved and the respective chemical treatment programs employed. The frequency of testing may range from hourly to perhaps monthly, again depending on the type of boiler operation. 

The monitoring work to be performed (such as measuring the rate of dirt pickup), the frequency of testing, and the sampling points... 

The frequency of testing of a reference substances depends on the known or suspected stability and of its prescribed use. Reference substances used as assay standards are re-examined on a two-yearly basis whilst the other reference substances are... 

Clinical trials for biotechnologically derived pharmaceuticals may be more complex than those for conventional pharmaceuticals and so the route and frequency of test... 

From this assessment Table 3 can then be used to determine the level and frequency of testing. From the example of FMECA in Table 4, the following actions should be performed ... 

Contract analytical testing can be utilized for purity, potency, sterility, and pyrogenic-ity testing. The frequency of testing is generally related to the volume and frequency of product preparation. 

The type and frequency of tests, analyses, and measurements to be made. 

Each dosage level, expressed in mg per kg of body weight or other appropriate imits, of the test or control article to be administered and the method and frequency of administration The type and frequency of tests, analyses, and measurements to be made The records to be maintained... 

Calibration or performance verification requirements, acceptance criteria, frequency of testing, and the actions required if the instrument, does not meet the performance verification requirements. 

For long-term studies, frequency of testing should be sufficient to establish the stability profile of the drug product. For products with a proposed shelf life of at least 12 months, the frequency of testing at the long-term storage condition should normally be every 3 months over the first year, every 6 months over the second year, and annually thereafter through the proposed shelf life. 

A minimum interval of three months between tests of each critical instrument loop is recommended in no case should the interval exceed 12 months. However, frequency of testing should be based on plant judgment and experience, as well as on Technology Center information. 

Periodic (at least monthly) microbiological analysis. This is to ensure the total bacterial count is kept under control. If higher than normal levels of bacteria are detected, the frequency of testing should be increased to weekly until control has been established. 

Increase the frequency of testing (i.e., number of test intervals) to determine whether or not the aberrant result is part of a new trend. 

Critical issues of concern include the identification of performance characteristics that need to be monitored and the frequency of test execution. In general, intervals be-... 

The long-term testing is required to be continued for a sufficient period beyond 12 months to cover all appropriate re-test periods. The frequency of testing should be... 

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