Free radical inhibition

Table 5. Free-Radical-Inhibiting Antioxidants or Reductants Useful in Cosmetics ...

K. F., Gorey, T.F. and Fitzpatrick, J.M. (1990). Free radical inhibition and serial chemiluminescence in evolving experimental pancreatitis. Br. J. Surg. 77, 1256-1259. 

The aggregation of platelets contributes to the development of atherosclerosis and to the formation of acute thrombus. The activated platelets that adhere to the vascular endothelium generate lipid peroxides and oxygen free radicals, inhibiting the endothelial formation of prostacyclin and nitric oxide. 

Anti-inflammatory activity. Extract of the green seed, administered externally to adult with skin inflammations by free radical inhibition at a concentration of 1%, was active . 

Kazinol F (31) Antioxidant activity (scavenging free radicals) Inhibition of tyrosinased [341 [34]... 

A previous investigation indicated that the pyrolysis of methyl 3-bromopropionate alone was autocatalyzed by the HBr gas product. However, under maximum free-radical inhibition the reaction was homogeneous, unimolecular and of first order111. Moreover, the acidity of the hydrogen adjacent to the COOCH3 was held responsible for the faster... 

Most generally, spur aspects appear whenever a chemically very active compound (essentially, electron scavengers) is present in the solid matrix, either as a normal constituent or as an additive. This has been demonstrated recently in a variety of irradiated polymers, where radiolysis of the matrix induces the production of either free radicals, inhibiting Ps formation by electron scavenging, or of trapped electrons, enhancing the Ps formation probability, depending on the temperature [41]. 

Doxorubicin . Intercalator, forms free radicals, inhibits topoisomerase Hodgkin s (ABVD), breast, endometrial, lung, ovarian CA BMS—delayed CHF (dexrazoxane is an iron-chelating agent preventing the formation of free radicals it is not a free radical trapper ), alopecia, vesicant, radiation recall ... 

The book starts with an introductory overview, which is intended to refresh the reader s memory on key aspects of free radicals and reactions thereof. Subsequent sections cover free radicals and food chemistry, natural antioxidants, and nutritional biochemistry and health. In the food chemistry section, topics range from analysis of free radicals within food matrices to Maillard reactions, emulsions, dairy, and meat products. In the antioxidant section, results are presented on the efficacy of antioxidants from tea, seeds, and selected naturally occurring compounds. Finally, in the nutritional biochemistry and health section, free radical inhibition is discussed in relationship to biochemical paths and cancerous cell cultures. 

The antioxidant effects of tannic acid have been recently demonstrated in a number of models of hepatotoxicity, free radical inhibition, NO production, and others. " ... 

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