4- formyl-3-thienyl methyl

Acrylic acid, -(3-benzo[f>]thienyl)-a -mercapto-reaction with iodine, 4, 764 Acrylic acid, o -cyano-y3-(2-thienyl)-ring opening, 4, 807 Acrylic acid, -formyl-in pyridazinone synthesis, 3, 46 Acrylic acid, furyl-rotamers, 4, 545 synthesis, 4, 658 Acrylic acid, 2-hydroxybenzoyl-chroman-4-one synthesis from, 3, 850 Acrylic acid, 5-(l-propynyl)-2-thienyl-methyl ester occurrence, 4, 909 Acrylonitrile... 

Formyl-3-thienyl Methyl Tellurium3 (Organo Lithium Method) A mixture of 55 mmol of butyl lithium and... 

Similar reactions starting with the ethylene acetals of 3-formyl- or 3-acetyl-2-thienyl dimethyl telluronium iodides yielded 3-formyl- or 3-acetyl-2-thienyl methyl tellurium. The acetals were hydrolyzed before the products were isolated2. 

Tellurium (3-Formyl-2-thienyl)-methyl- E12b, 440 (Het-TeR2 — Het-Te-R)... 

Formyl-3-thienyl Methyl Tellurium (Organo Lithium Method) A mixture of 55 mmol of butyl lithium and 7.8 g (50 mmol) of 4-formylthiophcnc ethylene acetal in diethyl ether is cooled at — 78° for 20 min. A solution of 14.5 g (50 mmol) of dimethyl ditellurium in diethyl ether is added dropwise until the orange color of the ditellurium persists in the mixture. The mixture is allowed to warm to 20° and is then poured onto ice/water. The product is extracted with diethyl ether, the extract is dried with anhydrous magnesium sulfate, filtered, the solvent is distilled from the filtrate and the residue is distilled under vacuum yield 6.3 g (50%) b.p. 120°/0.8 torr m.p. 55°. 

Scheme 9.12 shows the synthetic route. [4-Methyl-2,5-bis(trimethylsilylethy-nyl)-3-thienyl]heptafluorocyclopentene (31) was prepared from 3-bromo-4-methylthiophene (28) in three steps. 2 -methoxy derivative 33 was synthesized by the coupling of 31 with lithiated 32. After desilylation with KOH, Sonogashira coupling with bromoformyl compounds gave bisformylated diarylethenes 34. Formyl derivative 34 was converted into nitroxide radical 27a. 

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