1- methyl 2-thienyl

Acrylic acid, -(3-benzo[f>]thienyl)-a -mercapto-reaction with iodine, 4, 764 Acrylic acid, o -cyano-y3-(2-thienyl)-ring opening, 4, 807 Acrylic acid, -formyl-in pyridazinone synthesis, 3, 46 Acrylic acid, furyl-rotamers, 4, 545 synthesis, 4, 658 Acrylic acid, 2-hydroxybenzoyl-chroman-4-one synthesis from, 3, 850 Acrylic acid, 5-(l-propynyl)-2-thienyl-methyl ester occurrence, 4, 909 Acrylonitrile... 

Thieno[2,3-e]azaborine-6-carboxylic acid, 1,2-dihydro-2-phenyl-3-(2-thienyl)-methyl ester... 

CN N-[(5-chloro-2-thienyl)methyl]-A/ ,V-dimethyl-N-2-pyridinyl-l,2-ethanediamine... 

R1 = Ph, Bn, 2-furyl, 2-thienyl-methyl, 1-naphthyl-methyl, 4-MeOCH2C6H4, 2-, 3-, or 4-Tol, 4-CIC6H4, 4-N02C6H4, 4-MeOC6H4, 2-MeOC6H4 R2 = H, Me, Pr, Prn... 

Reduction of tri-(2-thienyl)methyl carbenium tetrafluoroborate by zinc in DME at 65°C produces, via the radical (341), two dimers (342) and (343). The former is the kinetically favored product, which changes to the thermodynamically preferred (343) on thermal equilibration. This obviously takes place by dissociation into the radical (341) (90TL2627). 

Similar reactions starting with the ethylene acetals of 3-formyl- or 3-acetyl-2-thienyl dimethyl telluronium iodides yielded 3-formyl- or 3-acetyl-2-thienyl methyl tellurium. The acetals were hydrolyzed before the products were isolated2. 

Tellurium (3-Formyl-2-thienyl)-methyl- E12b, 440 (Het-TeR2 — Het-Te-R)... 

Hydrazin 1,1 -Dimethyl-2-(2-thienyl-methyl)- E16a, 550 (Umlager.) Imidazol... 

Piperidin l-(5-Isopropy 1-2-thienyl-methyl)- -1-oxid IV/la, 299f. 2-Propanol 3-Diethylamino-l-phenylthio- Vl/la, 1, 388f. 

The scope of the reactions of 5-nitro-3-thienylethyl chloride and acetate with the lithium salt of 2-nitropropane to give (83) (cf. this series, Vol. 2, p. 80) has been investigated. The cyano-group was not found to be sufficiently active, since 4-cyano-2-thienyl-methyl and -ethyl chlorides only gave O-alkylated products by an mechanism. The iSn(AEAE) reaction also occurred between benzenethiolate and 4-nitro-2-thienylmethyl acetate, and a moderate yield of 4-nitro-2-thienylmethyl phenyl sulphide was obtained. 

Chlorothen. N-((S-Chloro-2-thienyl)methyl]-iV.AC-dimethyl-N-2-py ridinyl-lt2-ethanediamine 2-/(5-chloro-2-thenylH2-dimethylaminoethyl)amino]pyridine N. W-dimethyl -AT -(2 -py ridyl) -N -(5 -chloro -2 -thenyDeth -ylenediamine N,N-dimethy -N -(a-pyridyl)-N -(2-methyl-5-chlorothienyl)ethylenediamine iV-5-chtoro-2-thienyl-methyl-Ai AT -dimethyl -N-2-pyridylethylenediamine chlo-ropyrilene chloromethapyrilene chlorothcnylpyramine. C H,8C]N3S mo] wt 295.85. C 56.84%, H 6.13%, O 11.98%, N 14.20%, S 10.84%. Prepd by the condensation of 5-cNoro-2-theny] chloride and N,JV-dimethyl-JV -(2-pyrid-ylkthylenediamine in the presence of sodium or potassium amide Clapp et at., J. Am. Chem. Soc. 69, 1549 (1947). 

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