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Formalin-fixed, paraffin-embedded protocol development

The sample materials from which proteins for proteomics studies may be extracted include fresh or snap-frozen cells from varied sources such as biological fluids, (serum, urine, plasma) and solid tissues such as biopsy specimens. Moreover, proteins isolated from ethanol-fixed paraffin-embedded tissues can be utilized for MS analysis.2 Protocols for the identification of proteins from formalin-fixed paraffin-embedded (FFPE) tissues have been recently developed.3 4 FFPE materials are the most common forms of biopsy archives utilized worldwide, and represent an important advancement for the large-scale interrogation of proteins in archival patient-derived materials. Finally, laser capture microdissected tissues have been successfully used for MS analysis.45... [Pg.378]


See other pages where Formalin-fixed, paraffin-embedded protocol development is mentioned: [Pg.3]    [Pg.47]    [Pg.391]    [Pg.47]    [Pg.47]    [Pg.391]    [Pg.119]    [Pg.238]    [Pg.238]    [Pg.89]   
See also in sourсe #XX -- [ Pg.48 , Pg.49 , Pg.50 ]

See also in sourсe #XX -- [ Pg.48 , Pg.49 , Pg.50 ]




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Formalin

Formalin-fixed

Formalin-fixed, paraffin-embedded

Formalinization

Paraffin embedding

Protocol development

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