Food safety assessments

Smithing MP, Darvas F. Hazardexpert an expert system for predicting chemical toxicity. In Finlay JW, Robinson SF, Armstrong DJ, editors, Food safety assessment. Washington DC American Chemical Society, 1992. p. 191-200. 

Socaciu, C., Modern strategies of chemical control for food safety assessment Proceedings of International Symposium, USAMV, Cluj-Napoca, Bull. USAMV, 60, 34, 2004. 

Unlike the naturally occurring hormones for which human food safety assessment is based on a ratio of their amount consumed in food compared to their amount produced endogenously by the consumer, safety assessment for the synthetic trenbolone acetate and zeranol hormones is based on alternative... 

In some instances additional specialized studies may be required to assess drug-specific toxicological concerns. For example, hypersensitivity tests may be required for the -lactam antibiotics FDA has recently been concerned with how this standard human food safety assessment process accurately determines the safe concentration of antibiotic residues based on the traditional toxicological end-points. Of particular concern was the impact of low levels of antibiotics on the intestinal microflora. 

Proteins being at the center of cellular metabolism and development, it is to be expected that they focus a lot of interest in food safety assessment. They actually could negatively impact on human or animal health if they comprise, for example, polypeptidic allergens, proteinaceous toxins, and antagonistic proteins such as special inhibitors. For all these compounds, genome analysis would not bring pertinent information contrary to an in-depth proteome investigation (73). 

Food Safety Council. Proposed system for food safety assessment. Fd. Cosmet. Toxicol. 16(Suppl. 12),... 

Codex Alimentarius Commission. 2003. Alinorm 03/34 Appendix III. Guideline for the conduct of food safety assessment of foods derived from recombinant DNA plants. Annex IV. Annex on the assessment for possible allergenicity, Rome, Italy. 

Smithing, M.P. and Darvas, F., Hazard expert an expert system for predicting chemical toxicity, in Food Safety Assessment, Finlay, J.W., Robinson, S.F., Armstrong, D.J., Eds., American Chemical Society, Washington, D.C., 1992, pp. 191-200. 

Rulis, A. 1992. Threshold of Regulation Options for Handling Minimal Risk Situations. Food Safety Assessment, Edited by J.W. Finley, S.F. Robinson, and D.J. Armstrong (American Chemical Society, Symposium Series 484), 132-139. 

Figure 12-1 Proposed System for Food Safety Assessment. From Food Safety Council, 1982.

A Flavor Priority Ranking System / Acceptance and Intemationahsation - O. Easterday et al. in Food Safety Assessment, Chapter 16 (American Chemical Society, 1992)... 

OSTP (Office of Science and Technology Policy) (2002). Proposed Federal Actions to Update Field Test Requirements for Biotechnology Derived Plants and To Establish Early Food Safety Assessments for New Proteins Produced by Such Plants Notice. 67 Fed. Reg. 149 50577-50580. 

Kroes R, Kozianowski G, Threshold of toxicological concern (TTC) in food safety assessment, Toxicol. Lett. 2002 127 43-46. 

Scientific Committee, Food Safety Council. (1978). Subchronic Toxicity Studies. In "Proposed System for Food Safety Assessment". Fd Cosmet. Toxicol. Suppl. 2, 16 83-96. 

In a document entitled Proposed System for Food Safety Assessment , the Scientific Committee of the Food Safety Council (35) has attempted to delineate the steps by which decisions on safety or toxicity are arrived at. What is interesting about this approach is the departure from the traditional sequence of tests... 

Scientific Committee, Food Safety Council "Proposed System for Food Safety Assessment" Fd. Cosmet. Toxicol. 

General Principles of CM Food Safety Assessment j 363 These issues will be discussed in more detail in the following sections. 

High throu put screening for food safety assessment Biosensor technologies, hyperspectral imaging and practical ap catirms... 

Hammond, B.G., Rogers, S. G., Fuchs, R. L. Limitations of whole food feeding studies in food safety assessment. In Food Safety Evaluation. Organization for Economic Cooperation and Development, Paris, France 1993 pp. 85-97. 

Codex (2003b with Annexes II and III adopted in 2008), Guideline for the Conduct of Food Safety Assessment of Foods Derived from Recombinant-DNA Plants, CAC/GL 45-2003, available online at... 

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