Food idiosyncratic reactions

Safe drug therapy 5. Adverse drug reaction Patient has medical problem caused by an adverse drug effect, which may include a side effect as well as an allergic reaction idiosyncratic reaction and a dmg-drug, drug-food, or drug-laboratory test interaction. ... 

Idiosyncratic reactions. Any plant substance, whether used as food or medicine, has the potential to stimulate a negative response in unpredictably sensitive individuals. Safety classifications do not take into account such idiosyncratic responses, unless there is evidence to suggest that such an idiosyncratic reaction may be predictable. 

Food Herbs Safe, nontoxic herbs that can be taken in substantial quantities for continuous periods of time. Any substance can possibly cause an allergic reaction or idiosyncratic response. The first time you eat a new food or take a new herb, the dosage should be small and then gradually built up to the normal dosage. 

There are other adverse reactions to food for which the mechanism is not fully known. These reactions are identified as idiosyncratic pseudoallergic reactions with similar clinical symptomatology (Ring et al., 2001). Elicitors of this allergy-like... 

Despite the many biochemical and nutritional factors which can influence toxic response, it is reassuring that existing protocols used in safety evaluation, combined with appropriate safety factors, do appear to work in practice. It is much rarer to find adverse reactions in man ascribed to food additives under approved conditions of use than to naturally occurring constituents or contaminants of food. Where adverse reactions have been recognised, they have usually been due to idiosyncratic responses such as allergy to some synthetic food colours, and similar allergies have been found with naturally occurring alternatives, e.g. annatto. ... 

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