Molecular weight folic acid

Vitamins are vital (= vita) and mainly nitrogenous (= amines) substances of low-molecular weight. As a rule, they must be present in the diet as essential components. Only a few vitamins (e.g. A, K, Bi, B5, B12, folic acid, biotin) are formed in the intestine by bacteria. Plants constitute the main source of exogenous vitamin supply. In a biochemical context, the principal bio-catalytic effect of vitamins consists in substituting cofactors of enzymes which have undergone metabolic degradation. 

The molecular weight of folic acid is 441.40 g/mol. The molecule is very slightly soluble in water, quite soluble in the salt form and insoluble in alcohol. It is sensitive to light and ultraviolet (UV) radiation. Folic acid is readily soluble in dilute solutions of alkali hydroxides and carbonates. Aqueous solutions of folic acid are heat sensitive and decompose rapidly in the presence of light. Solutions should be stored in a cool place protected from light. 

Carbohydrates and vitamins are low-molecular ligands that recognize specific receptors on the cell surface (Lee et al., 2014). For instance, hyaluronic acid is a polymer of disaccharides composed of o-glucuronic acid and o-A-acetylglucosamine, which interacts with cluster determinant 44 receptors overexpressed on tumors. Acid folic is a vitamin that shows high affinity to the folate receptor that is also overexpressed on tumors. They have low-molecular weight, are relatively inexpensive to synthetize and results can be more reproducible due to the limited number of inherent structural diversities of the molecules. 

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