FMOC-C1

Bartok, T., Borsok, G., and Sagi, F., RP-HPLC separation of polyamines after automatic FMOC-C1 derivatization and precolumn sample clean-up using column switching, /. Liq. Chromatogr., 15, 777, 1992. 

H Godel, P Seitz, M Verhoef. Automated amino acid analysis using combined OPA and FMOC-C1 precolumn derivatization. LC-GC Inti 5 44-49, 1992. 

Since the early detection of amino acids with ninhydrin, many derivatization procedures have investigated these solutes. 4-Dimethylaminoazobenzene-4 -sulfonyl chloride (DABS-C1) is performing well, but the best seems to be FMOC (9-fluorenyl chloroformate) (63). More generally, each class of reactions replaces the active hydrogens of the OH, NH, and SH groups. 

Chemical building blocks Boc-Lys(Boc)-OH, 4-bromomethyl-3-nitrobenzoic acid, Ra amines A1-A7, Boc-statines B1-B3, Fmoc-amino acids C1-C31, and acylating agents D1-D20 (Fig. 8). 

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