Fluoroquinolones in children

The fluoroquinolones are contraindicated in patients with a history of hypersensitivity to the fluoroquinolones, in children younger than 18 years, and in pregnant women (Pregnancy Category C). These drugs also are contraindicated in patients whose life-styles do not allow for adherence to the precautions regarding photosensitivity. 

Wliat are the risks of using tetracyclines and fluoroquinolones in children are alternatives available ... 

Risks of using tetracyclines and fluoroquinolones in children must be weighed carefully against the risk for developing a life-threatening disease due to B. anthracis. Both agents can have adverse health reactions in children. If adverse reactions are suspected, theiapy may be changed to amoxicillin or penicillin. 

Susceptibility factors Children The evidence for quinolone-induced arthropathy in children has been reviewed [33 ]. Data from animal studies and case reports, including tendon-related adverse reactions seen in adults, support a policy of restricting the use of fluoroquinolones in children and adolescents. The emergence of fluoroquinolone-resistant pneumococci is another reason for restricting their use. The authors cited statements from the American Academy of Pediatrics on cases in which... 

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