Fluoro-DL-phenylalanine

Selection of these regulatory mutants is often done by using toxic analogues of amino adds for example p-fluoro-DL-phenylalanine is an analogue of phenylalanine. Mutants that have no feedback inhibition or repression to the amino add are also resistant to the analogue amino add. They are therefore selected for and can be used to overproduce the amino add. Some amino add analogues function as false co-repressors, false feedback inhibitors or inhibit the incorporation of foe amino acid into foe protein. 

To achieve overproduction of phenylalanine, the micro-organism should be derepressed at the pheA level and free of inhibition at the arcG level. Both genes are located on the chromosomal DNA of the micro-organism and, by means of amino add analogues such as p-fluoro-DL-phenylalanine, it is possible to make (phenylalanine) feedback resistant mutants of E.cdi (pheA and oroF mutants). The following procedure can be used ... 

C11H12FN03 N-acetyl-4-fluoro-DL-phenylalanine 17481-06-0 25.00 1.2317 2 21997 C11H13N04 5-[(2-methoxyphenoxy)methyl]-2-oxazolidinone 70-07-5 22.50 1.1975 2... 

Alanine, 3-(p-fluorophenyl)-, DL-. See 4-Fluoro-DL-phenylalanine Alanine glutamate CAS 13187-90-1... 

D,L-Fluorophenylalanine DL-3-(p-Fluorophenyl) alanine DL-4-Fluorophenylalanine DL-p-Fluorophenylalanine p-Fluoro-D,L-phenylalanine. See 4-Fluoro-DL-phenylalanine 2-Fluoro-phenylamine. See 2-Fluoroaniline 4-Fluoro-phenylamine. See 4-Fluoroaniline 4-Fluorophenyl bromide p-Fluorophenyl bromide. See 1-Bromo-4-fluorobenzene N-p-Fluorophenyl-2,3-dichloromaleimide. See 2,3-Dichloro-N-4-fluorophenylmaleimide 1-(4-Fluorophenyl)-2-methyl-2-morpholino-1-propanone CAS 209127-01-5 Uses Photoinitiator for coatings Trade Name Synonyms Greatcure 907F [Hunan Xinyu http //www.hunanxlnyu.com]... 

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Phenylalanine, synthesized from [ C]cyanide by the Bucherer modification of the Strecker synthesis, was resolved into its l- and D-iso-mers by the action of the d- and L-amino acid oxidases, respectively. The optically active amino acid was separated from phenylpyruvic acid by cation exchange chromatography (3). Similarly, DL-[ F]acyl-p-fluoro-phenylalanine has been subjected to stereospecific deacylation with the fungal enz)nne, L-amino acylase enz)nnatically generated L-[ F]p-fluoro-phenylalanine was separated from the D-acyl amino acid by column chromatography (4). 

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