Flow cytometry study

Antiproliferative assay, flow cytometry studies, in vivo activities and biomarkers determination represent key tools for profiling the phenotypic response to molecular or pharmacologic perturbation at cellular or tissue levels the study enables therapeutic response irrespective of target activity of topi and taken together, these results suggest that there is a strong potential for edotecarin in clinical [36, 37] development for treatment of human tumors. 

Dachary-Prigent, J., Freyssinet, J.M., Pasquet, J.M., Carron, J.C. and Nurden, A.T., 1993, Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation a flow cytometry study showing a role for free sulfhydryl groups. Blood, 81 2554-2565... 

Midoux, P., Mayer, R. and Monsigny, M. (1995) Membrane permeabilization by alphahelical peptides a flow cytometry study. Biochim. Biophys. Acta, 1239, 249-256. 

Fig. 8.14. Reprinted with permission of John Wiley Sons, Inc. 1990 from Darzynkiewicz Z and Traganos F (1990). Multiparameter flow cytometry studies of the cell cycle. Melamed MR, et al. (eds). Flow Cytometry and Sorting. New York Wiley-Liss, pp 469-501.

Another flow cytometry study involved the measurement of capacitance changes due to varied amounts of polarizable cellular DNA [884],... 

A two-phase air-liquid flow was developed on a PDMS chip (see also Chapter 3, section 3.1.2). It was found that the focused two-phase flow was stable in hydrophobic channels (down to 6 mL/h) see Figure 8.38. Below this flow rate, the sample column no longer maintained its integrity and broke up. This method was used to provide aerodynamic focusing of myoblast cells (C2Ci2) for the flow cytometry study. The cells, which were labeled with Syto 9, was focused and counted in the chip at a rate of 100 cells/s [382]. 

Dihydroarcyriarubin C (104), a new bisindole alkaloid, has been isolated from fruit bodies of a myxomycete Arcyria ferruginea, which was collected at Hao, Yasu-cho, Kochi Prefecture, together with two known bisindoles, arcyriarubin C (2) and arcyriaflavin C (4), and the structure of 104 was elucidated by spectral data. Arcyriaflavin C (4) was also obtained, together with arcyriaflavin B (3), from fruit bodies of Tub if era casparyi, which ( 16839) was collected at Mt. Miune, Monobe-mura, Kochi Prefecture, in November 1997. Arcyriaflavin C (4) was revealed to exhibit cell cycle inhibition activity on HeLa cells on the basis of flow cytometry studies. Fruit bodies of Fuligo Candida, which ( 23446) was collected at Motoyama-cho, Kochi Prefecture, in August 2002, were revealed to contain a relatively high quantity of cycloanthranilylproline (105). 

Nacife, V. P., Soeiro, M. D. N. C., Araujo-Jorge, T. C., Neto, H. C. C., and Meirelles, M. D. N. L. (2000). Ultrastructural, immunocytochemical and flow cytometry study of mouse peritoneal cells stimulated with carrageenan. Cell Struct. Fund. 25,337-350. 

Neubauer H, GUnesdogan B, Hanefeld C, Spiecker M, Mugge A Lipophilic statins interfere with the inhibitory effects of clopidc el on platelet function - a flow cytometry study Eur... 

Walrand, S. Valeix, S. Rodriguez, C. Ligot, R Chassagne, J. Vasson, M. Flow cytometry study of polymorphonuclear neutrophil oxidative hurst a comparison of three fluorescent prohes. Clin. Chim. Acta 2XSQ2, 331,103-110. 

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