Flounder, southern

FIGURE 2.18 Metabolism of benzo[a]pyrene by southern flounder. 

Little PJ, MO James, JB Pritchard, JR Bend (1984) Benzo(a)pyrene metabolism in hepatic microsomes from feral and 3-methylcholanthrene-treated southern flounder, Paralichthys lethostigma. J Environ Pathol Toxicol Oncol 5 309-320. 

Southern flounder, Paralichthys lethostigma-, South Carolina 1990-93 whole... 

Eggens, M., Bergman, A., Vethaak, D., Van der Weiden, M., Celander, M., Boon, J.P. (1995). Cytochrome P4501A indices as biomarkers of contaminant exposure results of a field study with plaice (Pleuronectes platessd) and flounder Platichthys flesus) from the southern North Sea. Aquatic Toxicology, 32 211-225. 

Table Till. Metabolism And Excretion Of Carboxylic Acids ly Southern Flounder...

In Vitro Studies. An assay for measuring taurine N-acyltransferase activity with C-phonylacetyl CoA as substrate has boon described (79). Enzyme activity was located In the matrix of the mitochondrion and was usually higher In kidney than liver for the nine fish species studied. Studies with Isolated renal tubules from the winter flounder and the southern flounder (84 and James and Pritchard, unpublished) have shown that added phenylacetlc acid and benzoic acid were extensively metabolized to their taurine conjugates during a 60 minute Incubation. 

To summarize, several studies have demonstrated the ln iortance of conjugation reactions in determining the fate of xenobiotics in aquatic am mala. Among fish, most Information had been gained in the trout, the southern flounder, the winter flounder and the dogfish shark. It is evident that there are considerable Interspecles differences in the ability of fish to conjugate xenobiotics, as is true for other species, but the major pathways of conjugation are similar in all animal species studied. 

Aquarium assay format This assay format has been widely used in Pfiesteria studies to assess toxicity of Pfiesteria spp. or its derived products by exposing fish to either Pfiesteria spp. containing environmental sediments, water samples, or clonal Pfiesteria cultures. Several formats and variants of the fish bioassay have been reported that differed in the use of various experimental fish and shellfish species (tilapia, hybrid striped bass, southern flounder, eel, menhaden, sheepshead minnow, blue crab, bay scallop, and eastern oyster), and assay conditions, including salinity, the size, age, and density of fish, aquarium size, and time course [4,15,17]. 

FAULK c K and holt h (2009) Early weaning of southern flounder, Paralichthys lethostigma, larvae and ontogeny of selected digestive enzymes. Aquaculture 296, 213-218. 

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