Flos daturae

The on-line coupling of CE with electrospray ionization mass spectrometry (CE-ESI-MS) allows high separation efficiency together with high sensitivity and selectivity as well as molecular structural information. A CE-UV-ESI-MS method was developed for the analysis of hoscyamine, scopolamine, and other tropane derivatives [131]. The differentiation of hyoscyamine from littorine, commonly encountered in plant material, was demonstrated using in-source collision-induced dissociation. The developed method was applied to the analysis of these alkaloids in Belladonna leaf extract and in Datura Candida x D. awreahairy root extract. Recently, CE coupled with electrochemiluminescence detection has been used for the determination of atropine and scopolamine in Flos daturae [132]. 

Li, J., Chim, Y. and Jua, H. (2007) Simultaneous electrochemilmniniscence detection of anisodamine, atropine and scopolamine in Flos daturae by capillary electrophoresis using b-cyclodextrin as additive. Electroanalysis. 19, 1569-1574. 

Gao Y, Tian YL, Wang EK (2005) Simultaneous determination of two active ingredients in Flos daturae by capillary electrophoresis with electrochemiluminescence detection. Anal Chim Acta 545(2) 137-141. doi 10.1016/j.aca.2005.04.071... 

Hyoscine-containing plants have been used for centuries in traditional Chinese medicine as anesthetics. Hyoscine from Flos daturae (flowers from Datura species) has been used as a general anesthetic in China (jIANGSU). ... 

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