Final Comments and Future Perspectives

Due to their biocompatibility and biodegradability, PLA, PLGA and chitosan have been shown to be excellent delivery carriers for controlled administration of drugs, peptides and proteins. [Pg.450]

Another important point to be taken into account is the toxicology of the generated carriers, especially in the nanometer-size scale. A new subdiscipline known as nanotoxicology has come into sight because the interactions of nanocarriers with biological systems are really complex and the size and surface properties of nanocarriers modify the behavior of these components in the body. Toxicology studies and regulations are necessary in order to fully define the biocompatibility of nanocarriers in humans. [Pg.450]

Uhrich, et al. Polymeric systems for controlled drug release. Chemical Reviews, 99 (11) 3181-3198, 1999. [Pg.450]

Laurencin, Biodegradable polymers as biomaterials. Progress in Polymer Science, 32 (8-9) 762-798, 2007. [Pg.450]

Anderson, and M.S. Shive, Biodegradation and biocompatibility of PLA and PLGA microspheres. Advanced Drug Delivery Reviews, 28 (1) 5-24,1997. [Pg.450]

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