Fibrous instabilities

Collect particulate material by either filtration or centrifugation. 

Transfer to microscope slide and visually compare with Fig. 17.3. 

Fibrous materials found in bottled wines are usually cellulose, originating from the filter pad matrix or from case lint that may find itself in bottles prior to filling. Case lint containing lignin will appear microscopically as red fibrous material. However, all cellulose material appears light-blue under the zinc/iodine stain. For the zinc/iodine stain (similar to the 

Herzberg stain), best results are obtained when the preparation is examined fresh because the color intensity diminishes after 30min (Quinsland, 

Asbestos fibers are not stained using either of these stains. 

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At autopsy, a ruptured plaque features a thin fibrous cap overlying cell-rich regions with a lipid-rich necrotic core (<3 mm ) containing cell debris. The indicators for plaque instability include an inflammatory infiltrate with lipid-rich macrophages (foam-cells) and a decreased collagen and smooth muscle cell (SMC) content in the fibrous caps as well as at the shoulders of the atheroma, respectively. Therefore, one of the challenges of modern medicine is the design of... 

Furthermore, Ang n has been found to contribute to VSMC senescence, which has been implicated in the pathogenesis of atherosclerosis (Kunieda et al. 2006). Cell senescence may promote plaque instability, since loss of VSMCs leads to transformation into a rupture-prone plaque with a thin fibrous cap over the lipid-rich core (Geng and Libby 2002). 

The electrospinning of poly(s-caprolactone) (PCL) solutions have been reported by Reneker et al. [74]. They varied the PCL solution concentrations between 14 and 18 wt%. The instability in the electrospinning of PCL results in the contact and merging of segments in different loops of the electrospinning jet to form garlandlike fibrous structures [74]. Yoshimoto et al. [75] have studied the potential of electrospun PCL fiber mats for use in bone tissue engineering. They found that the... 

On occasion, nonmicrobial sediment and/or hazes may develop in bottled wines and juices. Inasmuch as some of these may, upon microscopic examination, appear bacterialike the following section is included to assist the reader in their identification. For the sake of discussion, instabilities may be classified as particulate, including crystalline (or crystallike), fibrous, and amorphous which lack regular structural properties (See Table D-1). 

Mechanical instabilities allow micro-movements between the anchoring parts of the implant and the adjacent bone that triggers the replacement of bone by fibrous connective tissue. 

Nonmicrobial instabilities can be classified as crystalline, crystallike, fibrous, or amorphous (Table 17.1). To determine the cause of the precipitation, preliminary sample evaluation and review of processing records may be helpful. If small amounts of sediment or haze are present, it may be necessary to first concentrate the material by either centrifugation or benchtop filtration. Alternatively, the bottle may be stood upright for several hours and the precipitate carefully collected for analysis. 

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