Fibroblast growth factors components

Rogelj, S., Klagsbrun, M., Atzmon, R., Kurokawa, M., Hai-movitz. A., Fuks, Z. and Vlodavsky, 1. (1989) Basic fibroblast growth factor is an extracellular matrix component required for supporting the proliferation of vascular endothelial cells and the differentiation of PC 12 cells. J. Cell. Biol. 109 823-831. 

Figure 19.1 Cardiac tissue engineering triad. Schematic representation of the interplay between the components of the cardiac tissue engineering triad. Biomaterials are key components for cardiac tissue engineering applications and play a critical role in this technology. MSC, mesenchymal stem cell ADSC, adipose stem cell iPS, induced pluripotent cell CPC, cardiac progenitor cell VEGF, vascular endothelial growth factor FGF, fibroblast growth factor NRG, neuregulin EPO, erythropoietin HGF, hepatocyte growth factor SDF-1, stromal cell—derived factor 1.

With its hydrophilic and cationic nature, and its structure analogous to glycosaminoglycans, CS is expected to be endowed with related biological activity [32-34], hi fact, CS exhibits interactions with ECM components, immune cells, and growth factors such as the fibroblasts growth factors [35]. CS has a number of other desirable properties for a tissue scaffold it has anticoagulant properties and antibacterial and antifungal action [36]. 

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