Fiat disease

The disease is usually diagnosed by adolescence, and patients exhibit tall stature and a variety of skeletal deformities, inciuding very iong, thin bones of the digits and iimbs fiat feet scoiiosis and breastbone deformation. 

Beginning with the fiat worms, and proceeding at once to the flukes, we come to the most devastating worm diseases of all, those caused by flukes in the blood, particularly schistosomiasis, whose natural history is sketched in Section i.i (p. ii). Depending on the species, the remedy of first choice is either niridazole (6,24) or an organic antimonial (see Table 4.4, p. 132 also Section 12.0). Also an organic phosphate, metriphonate (12.24) (dimethyl 2,2,2-trichloro-i-hydroxyethylphosphonate), which selectively inhibits the worm s acetylcholinesterase, provides a useful supplement to the treatment. The greatest need is to find an efficient and safe prophylactic. 

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