Fetal inflammatory responses

Of all the likely prenatal factors in cerebral palsy, reduced blood flow to the fetal brain (cerebral ischemia) during gestation is the most important. The second most important is apparendy inflammation caused by intrauterine infection.12 Fetal inflammatory responses can evidendy contribute to brain injury by producing white matter lesions. In any case, inflammation resulting from infection of the chorio-amnion membrane system that surrounds the fetus (chorioamnionitis) is now a known causative factor for neurological disturbance and cerebral palsy. 

Specifically, aloe contains a carboxypeptidase that is responsible for degrading bradykinase (Fujita et al., 1979). A later study on homogenized fetal calf skin showed that both aloe gel and aloe extract in increasing amounts inhibited the oxidation of arachidonic acid, which suggests inhibition of production of inflammatory prostaglandins (Penney s, 1982). As discussed in section 24.4.4, some aloe constituents to salicylic acid (Robson et al., 1982). 

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