Ferula jaeschkeana

Singh, M. M., A. Agnihotri, S. N. Garg, S. Agarwal, D. N. Gupta, G. Keshri, and V. P. Kamboj. Antifertility and hormonal properties of certain carotene sesquiterpenes of Ferula jaeschkeana. Planta Med 1988 54(6) 492-494. 

Sriraman M C, Nagasampagi B A, Pandey R C, Sukh Dev 1973 Studies in sesquiterpenes. XLIX. Sesquiterpenes from Ferula jaeschkeana Vatke (Part 1) jaeschkeanadiol - structure, stereochemistry. Tetrahedron 29 985-991... 

Cineole, 13, is a natural herbicide [73]. Its hydroxy derivative 14 (2-hydroxy-1,4-cineole 1,4-epoxy-p-menthane-2-ol) is a constituent of oil from rhizomes of Ferula jaeschkeana [74]. Its 2-methylbenzyl ether 15 (cinmethylin) is a preemergence grass herbicide [75, 76]. Alcohol 14 can be prepared by microbial hydroxy-lation of 13 [77]. This also produces ketone 16 and its enantiomer [78]. The fragrance of ketone 16 and isomeric l-isopropyl-4-methyl- 7-oxabicyclo[2.2.1] heptan-2-one is very similar to that of 14 and menthone [79]. Mullilam diol 17, a dihydroxy derivative of 13, has been isolated from Zanthoxylum rhetsa, a plant that exhibits antibiotic activity which is prescribed in dyspepsia and diarrhea. The eight-carbon system rengyoxide has been found in Forsythia suspensa fruits [80] (Fig. 4). 

Isol. from plants, eg. Trametes suaveolens, Ferula jaeschkeana. Flakes (EtOH or Et20). Mp 48°. Bp 256°, Bp2o 160°. 

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