Ferrous Citrate

Ferrous Citrate occurs as a slightly gray-green powder or as white crystals. 

L-Carnitine Erythritol Ferric Citrate Ferrous Citrate Maltitol... 

Kawada A, Hiruma M, Noguchi H, Kimura M, Ishibashi A, Banba H, Marshall J. Photosensitivity due to sodium ferrous citrate. Contact Dermatitis 1996 34(1) 77. 

Ferrous Citrate, Several forms o( this salt are known. Prepn from citric acid and Fe powder Oroshnik, Haffcke, U,S. pat. 2,904,573 (1959 to Ortho) and ferrous salts Carlson, LI.S. pet. 3,091,626 (1963 to Scherer). 

A study in 6 patients found that neomycin markedly reduced the absorption of iron (iron as ferrous citrate) in 4 patients, but increased the absorption in the other 2 patients who initially had low serum iron levels. None of the patients were anaemic at any time. The importance of this is uncertain, but consider this possible interaction if the response to iron is poor. 

Iron (II) chloride (1 2). See Ferrous chloride Iron (III) chloride. See Ferric chloride Iron chloride hexahydrate Iron (III) chloride hexahydrate Iron (3+) chloride, hexahydrate. See Ferric chloride hexahydrate Iron chlorides. See Ferric chloride Iron (III) choline citrate Iron choline citrate complex. See Ferric choline citrate Iron chrome brown. See Chrome iron brown Iron citrate. See Ferric citrate Iron (II) citrate. See Ferrous citrate Iron (III) citrate. See Ferric citrate Iron cyanide. See Cl 77510 Iron dichloride. See Ferrous chloride Iron dicyclopentadienyl. See Ferrocene Iron, [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoa to(20)-,Nn hydroxy-. SeeHematin Iron dimethyidithiocarbamate Iron (III) dimethyidithiocarbamate. See Ferbam a-lrone... 

Cephalins Ethyl oleate Ferrous citrate L-Glutamic acid L-Histidine Iodine L-lsoleucine... 

Dichloro-p-phenylenediamine CeHeCle Lindane CeHeFN 2-Fluoroaniline 4-Fluoroaniline C6HeFe07 Ferrous citrate... 

To elucidate the direct effect of reactive oxygen species on dopamine transport, Fleckenstein et al. (1997) used xanthine oxidase to generate such species and found that oxygen radicals, like me-thamphetamine administration (Fleckenstein etal. 1997) diminish dopamine transporter 7max-Since dopamine tranporters are the primary means whereby dopamine is cleared from the synaptic cleft, disruption could lead to increased extracellular dopamine and ultimately the production of highly destructive reactive oxygen species. Dopamine clearance in rat striatum was decreased 7 days after an infusion of 1 [il of 4.2 nM ferrous citrate into the substantia nigra (Lin etal. 1998). Iron-... 

It is common practice not to add iron to TPN solutions because of the possibility of physical incompatibility and the risk of anaphylaxis when iron-dextran preparations are used. Fatal anaphylactic reaction secondary to intramuscular iron dextran injections (Becker et al, 1966), as well as other local and systemic reactions following intravenous administration, particularly using the bolus dosage method, have been described (Hamstra et al., 1980). Yet many recent reports attest to the low frequency of the above complications and the apparent safety of using lower doses in nutrient solutions for adults and children (Hamstra et al., 1980 Gilbert et al., 1979 Figueredo and Kaminski, 1979 Halpin et al., 1980 Peters et al, 1980 Reed et al, 1981). Similarly, physical incompatibility problems are less common with the lower doses and lower iron concentrations. As an alternative iron source, ferrous citrate may prove to be a more suitable intravenous iron supplement than dextran (Sayers et al, 1983). 

Sayers, M. H., Johnson, D. K., Schumann, L. A., Ivery, M. F., Young, J. H., and Finch, C. A., 1983, Supplementation of total parenteral nutrition solutions with ferrous citrate, J. Parent. Enter. Nutr. 7 117. 

Mohanakumar KP, de Bartolomeis A, Wu RM, Yeh KJ, Stemberger LM, Peng SY, Murphy DL, Chiueh CC. Ferrous-citrate complex and nigral degeneration evidence for free-radical formation and lipid peroxidation. Ann NY Acad Sci 1994 ... 

Sodium citrate at a pH of 4.0 was used to clean a service water system that was heavily scaled with iron oxide. The authors described the dissolution of iron oxide with either ammonium or sodium citrate. A precipitate of ferrous citrate was noted at a low (3.5) pH, but this precipitate dissolved at higher pH values. A 65,000-gal (246,025-L) cooling water system was cleaned with 10% sodium citrate. Recently there have been additional investigations of the use of sodium citrate. 

The major oxidizing agent for the EDTA system is FedIDEDTA, while the external oxidizer (oxygen, nitrite) oxidizes the copper in the iron citrate system. The external oxidizer does oxidize the ferrous citrate to ferric citrate, but this species does not dissolve much of the copper it actually acts as a sink for the external oxidizer. The only benefit of using the iron citrate solution is that an additional oxidizing fill of the unit is avoided. 

Strouse J (1977) C NMR studies of ferrous citrates in acidic and alkaline solutions. Implications concerning the active site of aconitase. J Am Chem Soc 99 572-580... 

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