Febrile convulsions vaccine

Neuralgic amyotrophy (12), febrile convulsions (13), and Guillain-Barre sjmdrome (14) have been attributed to hepatitis B vaccine. Fatal inflammatory polyradiculoneuropathy has been reported in temporal relation to hepatitis B administration (15). 

Jacobsen SJ, Ackerson BK, Sy LS, Tran TN, Jones TL, Yao JF, Xie F, Craig Cheetham T, Saddier P. Observational safety study of febrile convulsion following first dose MMRV vaccination in a managed care setting. Vaccine 2009 27 4656-61. 

In 1995, live virus Varicella vaccine (Oka strain) was licensed in the USA. Of the 6574 reported adverse events 4% (67.5 per 100 000 doses) after immunization were serious, while the majority were minor reactions, such as rash, redness, or injection site pain (9). About 10% of immunized children developed mild chickenpox. A total 193 vaccinees reported neurological symptoms, including Bell s palsy, convulsions, and demyelinating syndromes febrile seizures accounted for half of the cases of convulsions. There were 14 deaths, but a role for the vaccine was not proven. 

---