Fast-Atom Bombardment, or Liquid SIMS

Colton has described FAB as a method that provides the molecular results of static SIMS under the high-flux conditions of dynamic SIMS. It is now understood that the important feature of this technique is the liquid matrix, and not the neutral beam. Thus, the technique is more appropriately described as liquid SIMS. The liquid 

FIGURE 5.3 SIMS-TOF mass spectrum of the peptide dynorphin obtained by accumulation of the ion signal for 9 hours. (Reprinted with permission from reference 8). 

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