Falcaria vulgaris

The cicutoxin-like compounds are known for their extreme and violent toxicity. There are other plant species that contain these polyacetylene type compounds, however none are as toxic as cicutoxin and oenanthotoxin. These species all come from the Umbelliferae family and include Falcaria vulgaris, Slum sisarum, Carum carvi, Aegopodium podagraria and Daucus carota. Daucus carota is the common carrot and it contains a similar cicutoxin-like compound, caratotoxin, but is less toxic (LD50 = 100 mg/kg i.v. in mice) than cicutoxin. Caratotoxin is found in minute amounts in carrots and is not considered a health concern for humans (Crosby and Aharonson, 1967). 

Carum carvi, Conium maculatum, Falcaria vulgaris [root], Oplopanax chironium, Petroselinum crispum, Saposhnikovia divaricata (Apiaceae), Hedera helix (Araliaceae)... 

From the ether-soluble fraction, Takahashi etal. 134, 135) isolated sitosterol-P-D-glucoside, sitosterol, p-elemene (96), eremophilene (97) and a new polyacetylenic alcohol named panaxynol (98), the structure of which was elucidated as heptadeca-l,9(Z)-diene-4,6-diyn-3-ol by degradative and synthetic procedures. It is identical with carotatoxin from carrots 136) and falcarinol from Falcaria vulgaris 137). Recently two other polyacetylenic alcohols, 9,10-epoxy-3-hydroxyheptadeca-l-en-4,6-diyne [(99), panaxydol] 138) and heptadeca-l-en-4,6-diyn-3,9-diol (100) 139) were isolated from Ginseng roots by Wrobel et al. 

Present in the root of Falcaria vulgaris and in other species. 

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