Extrahepatic tissue specific organs

Many chemicals can alter the rate and/or the pathways of xenobiotic metabolism, both in hepatic and extrahepatic tissues. Exposure to these chemicals through environmental pollution, agriculture, natural sources, modern medicine and personal social habits is common. For toxins that are activated by metabolism, exposure to metabolic inducers or inhibitors can affect organ-specificity as well as overall sensitivity to a toxin. 

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