Extracellular transport

Antidepressant Drugs. Figure 1 Effects of stress as a model for depression and the reversal by the use of antidepressants. Multiple intracellular targets might be involved in the regulation of plasticity and resilience by antidepressants, which block extracellular transporters. Adapted from [1],... 

The free fatty acid uptake by tissues is related directly to the plasma free fatty acid concentration, which in turn is determined by the rate of lipolysis in adipose tissue. After dissociation of the fatty acid-albumin complex at the plasma membrane, fatty acids bind to a membrane tty acid transport protein that acts as a transmembrane cotransporter with Na. On entering the cytosol, free fatty acids are bound by intracellular fatty acid-binding proteins. The role of these proteins in intracellular transport is thought to be similar to that of serum albumin in extracellular transport of long-chain fatty acids. 

Russ, H, Staust, K, Martel, R, Gliess, M and Schomig, E (1996) The extracellular transporter for monoamine transmitters exists in cells derived from human central nervous system glia. Eur. J. 

Ved Brat, S.V. Williams, GM. (1982) Hepatocyte-mediated production of sister chromatid exchange in co-cultured cells by acrylonitrile evidence for extracellular transport of a stable reactive intermediate. Cancer Lett., 17, 213-216... 

The final type of calcification mechanism involves some form of extracellular transport system which avoids all the transcellular energy barriers. As a concept, it is extremely valuable but it needs redefining of its relation to the ions under consideration and the motive forces for their movement. 

Golgi apparatus. A complex series of double-membrane structures that interact with the endoplasmic reticulum and that serve as a transfer point for proteins destined for other organelles, the plasma membrane, or extracellular transport. 

Yuan, F., Krol, A. and Tong, S. (2001) Available space and extracellular transport of macromolecules Effects of pore size and connectedness. Ann. Biomed. Eng., 29,1150-1158. 

Biotemplates have been fabricated from two-dimensional crystalline surface proteins for the subsequent electrochemical deposition of nanowire structures [82]. These surface layer proteins encapsulate certain bacterial cells, controlling extracellular transport. They form especially robust thin films over cells, and are resistant to conditions that normally denature proteins, such as low pH and heat, thus making them ideal as template materials for electrodeposition. Schwartz and coworkers investigated a hexagonally packed intermediate surface layer protein from... 

Each class of lipoprotein has a characteristic protein and lipid composition and functions In the cellular export, extracellular transport through the circulatory system, and receptor-mediated cellular Import of lipids (see Table 18-3 and Figure 18-13). 

Figure 6.3 Illustration of an assembly model and the extracellular transport of spider silk major ampullate (MAA) protein in orb web spiders. (Reprinted with permission from Ref [7], Copyright (2005) Elsevier.)...

Wang Y, Yuan F. Delivery of viral vectors to tumor cells Extracellular transport, systemic distribution, and strategies for improvement. Ann Biomed Eng 2006 34 114-127. 

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