Extended multiplicative signal

In the previous section, it was noted that the MSC method is expected to perform poorly in cases where spectral offset and multiplicative variations are very small relative to those obtained from chemistry-based variations. In response to this, several methods were developed to enable more accurate multiplicative corrections through better modeling of chemistry-based variations in the data [34-35]. One such method is an extension of the MSC method, appropriately called extended multiplicative signal correction (EMSC) [35-37]. 

H. Martens and E. Stark, Extended multiplicative signal correction and spectral interference subtraction new preprocessing methods for near infrared spectroscopy, J. Pharm. Biomed. Anal, 9, 625-35 (1991). 

H. Martens, J.P. Nielsen and S.B. Engelsen, Light scattering and light absorbance separated by extended multiplicative signal correction. Application to near-infrared transmission analysis of powder mixtures, Anal Chem., 75, 394 (2003). 

EMSC extended multiplicative signal IQ/OQ/PQ installation qualification/operation... 

Kohler, A., Zimonja, M., Segtnan, V., and Martens, H. (2009). Standard normal variate, multiplicative signal correction and extended multiplicative signal correction preprocessing in biospectroscopy. In "Comprehensive Chemometrics", (S. D. Brown, R. Tauler, and B. Walczak, Eds), Vol. 2, pp. 139-162. Elsevier, Amsterdam. 

Martens, H. and Stark, E., Extended Multiplicative Signal Correction and Spectral Interference Subtraction New Preprocessing Methods for Near Infrared Spectroscopy /. Pharm. Biomed. 

This resonant Mie scattering effect is the cause of the phenomenon previously referred to as the dispersion artefact , which was an inaccurate description because the effect was not solely due to dispersion and it is not an artefact because it can be explained fully. With an understanding of the physics behind resonant Mie scattering, preliminary algorithms based on the extended multiplicative signal correction (EMSC) have been developed. The EMSC... 

Resonant Mie Scattering Correction using the Extended Multiplicative Signal Correction (RMieS-EMSC)... 

Afseth NK, Kohler A. Extended multiplicative signal correction in vibrational spectroscopy, a tutorial. Chemometr Intell Lab 2012 117 92-9. 

The detection of a specific gas (10) is accompHshed by comparing the signal of the detector that is constrained to the preselected spectral band pass with a reference detector having all conditions the same except that its preselected spectral band is not affected by the presence of the gas to be detected. Possible interference by other gases must be taken into account. It may be necessary to have multiple channels or spectral discrimination over an extended Spectral region to make identification highly probable. Except for covert surveillance most detection scenarios are highly controlled and identification is not too difficult. 

Like always in NMR 118), when the single-scan signal-to-noise ratio SjN) is insufficient for a precise evaluation of the acquired data, it can be enhanced by averaging or, more frequently, accumulating, of data sets obtained in a number of repeated scans. Multiple-scan data accumulation also opens a number of novel experimental possibilities extending beyond... 

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