Exposure prolonged

Symptoms of exposure Prolonged exposure may cause eye irritation. May damage cornea on contact. Contact with skin may cause irritation, ulceration, and necrosis (Patnaik, 1992). An irritation concentration of 2.00 mg/m in air was reported by Ruth (1986). 

Unlikely to cause Irritation to skin on single exposure. Prolonged exposure may defat the skin leading to dermatitis. 

Inorganic acids have similar acute toxic properties corrosive action on the skin, the respiratory tract, and especially the eyes where corneal damage may occur. Severe exposures may cause blindness, pulmonary edema, and even death. The onset of symptoms may be delayed for several hours after exposure. Prolonged exposures to low concentrations produce chronic effects such as tooth erosion, chronic bronchitis, and photosensitization of the skin (J >2, ). 

BZ easily crosses the blood-brain barrier leading to mostly CNS effects. Signs are dependent on the dose and time post-exposure. Prolonged effects may occur depending on the dose of BZ absorbed. Tachycardia and dry mouth develop within 15 min to 4 h after exposure (Anonymous, 1998). Peak effects occur at 8 to 10 h (Anonymous, 2001). 

In case of eye contact, the corrosive should be diluted by irrigating the area with tap water or saline for 30-60 min. With alkali exposures prolonged irrigation may be necessary. 

With the typical dimethoxy and dicthoxy structure of pesticides, aging rates arc such that the phenomenon only becomes a problem when treatment is delayed and/or exposure prolonged. It i.s commonly, but erroneously, believed that 1 day after intoxication with an OF insecticide virtually all the phosphorylaicd enzyme will be in the t cd fonn so that oxime therapy will be ineffective after this time. However, this interpretation derives from in vitro. studies in which AChE is rapidly inhibited and is maintained fully inhibited thereafter by the pre.scncc of an excess of inhibitor and in the absence of oxime throughout the experiment. Such experiments do not represent the case in 1 ivo and should not be used as a reason to abandon the use of oxime therapy after 24 hr. 

Carbon monoxide is a highly poisonous gas. The acute toxic symptoms include headache, tachypnea, nausea, dizziness, weakness, confusion, depression, hallucination, loss of muscular control, and an increase and then a decrease in pulse and respiratory rate. If the dose is high, these symptoms progress to collapse, unconsciousness, and death. The severity of toxic effects depends on the concentration of carbon monoxide and the duration of exposure. Prolonged exposure to a concentration of 50 ppm does not result in adverse health effects in humans, but a... 

Absorption route Can enter the body by inhalation or ingestion. Immediate eftoels Irritates the eyes and respiratory tract. Elfects of prolenged/repeated exposure Prolonged exposure to particles can cause lung disorders. ... 

Abaorpllon route Can enter the body by inhalation or ingestion. Evaporation negligible at 20 C. but harmful atmospheric concentrations of airborne particles can build up rapidly. Immediate effects Corrosive to the eyes, skin and respiratory tract. Inhalation can cause lung edema. In serious cases risk of death. Effects of prolongsd/repeeted exposure Prolonged or repeated contact can cause skin disorders. Has been found to cause a type of lung cancer in certain animal species under certain circumstances. ... 

Absorption routs Can enter the body by Inhalation or ingestion or through the skin. Harmful atmospheric concentrations build up fairly slowly on evaporation, but much more rapidly In aerosol form. Immediate effects Irritates the eyes, skin and respiratory tract. Liquid destroys the skin s natural oils. Affects the nervous system. Inhalation can cause severe breathing difficulties (asthma). In serious oases risk of seizures and unconsciousness. Effeota of prolonged/repeated exposure Prolonged or repeated contact can cause skin disorders. Can cause kidney damage. ... 

Absorption route Can enter the body by inhalation. Harmful atmospheric concentrations can build up very rapidly if gas is released. Immediate ects Corrosive to the eyes, skin and respiratory tract. Inhalation of vapor/fumes can causa lung edema. Can affect the upper respiratory tract, causing nose-bleed. Can cause death. Keep under medical observation. Effects of prolonged/repeated exposure Prolonged or repeated contact to gas/fumes can cause lung disorders. Can affect the kidneys. ... 

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