Experiments necessary for scale-up

The reactor conditions that we measure should always include flow rates in the reacting phase, or of one phase relative to the other, since the actual dimensions of a reactor with a given capacity, are directly related to the rates of the flows passing through the reactor. The experiments indicated so far should give us an accurate idea of the reaction rates per unit volume of a reactor, for a range of conditions. Then the real scale-up problems start. 

The scale-up problems become much more difficult if the large scale reactor differs considerably from these ideal models. Notorious examples are fluidized bed reactors without internals, stirred tanks where the macro mixing is rate determining, and reactors filled with solid material where large temperature gradients exist, such as coke ovens and blast furnaces, and some catalytic gas-phase processes. 

---

THE PATH OF CHEMICAL REACTOR DEVELOPMENT 2.4. Experiments necessary for scale-up... 

---