Experimental Approaches Towards Proton-Coupled Electron Transfer Reactions in Biological Redox Systems

Experimental Approaches Towards Proton-Coupled Electron Transfer Reactions in Biological Redox Systems 

SIBYLLE BRENNER/ SAM HAY, DERREN J. HEYES AND NIGEL S. SCRUTTON  

Manchester Interdisciplinary Biocentre and Faculty of Life Science, University of Manchester, Manchester, UK 

Proton-coupled electron transfer (PCET) reactions play a fundamental role in the respiratory chain and in photosynthesis. In both membrane-bound systems, an electrochemical gradient is built up across the lipid bilayer by separating protons from electrons the resulting chemiosmotic proton potential serves to fuel a proton-driven pump synthesising the universal biological energy equivalent ATP (adenosine triphosphate). In addition to the relevance of PCET in these energy conversions, the coupled transfer of electrons and protons is an 

Proton-Coupled Electron Transfer A Carrefour of Chemical Reactivity Traditions 

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