Excretion of Gonadotropic Hormones

Salmon and Hamblen (1943) studied the recovery in the urine of chorionic gonadotropin injected intravenously into rabbits. Excretion was terminated after 96 hours, the total amount excreted reaching 5.7%. The bulk was excreted within 24 hours. 

The urinary excretion of injected chorionic gonadotropin ranges, on an average, between 5-10%, In rare cases more has been observed. The values found by different authors are given in Table IV. 

A considerable delay of resorption and urinary excretion of chorionic gonadotropin has been obtained with chorionic gonadotropin tannate. The bulk of excretion (5%) was observed on the following days after administration  

Chorionic gonadotropin injected into pregnant rabbits is selectively stored in their placentae, but is not excreted into the urine or the amniotic or allantoic fluids. Human placenta stores and adsorbs chorionic gonadotropin. 

Pregnant mare blood gonadotropin appears in the urine only in traces because of its molecular size. 

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