Excipient powders

Staniforth, J. N., and Patel, C. J. (1989), Creep compliance behavior of direct compression excipients, Powder Technol., 57, 83-87. 

Besides the use of excipients, powder flow and dispersion can also be improved by manipulation of the physical characteristics of the powder. 

Rowley, G. Mackin, L.A. The effect of moisture sorption on electrostatic charging of selected pharmaceutical excipient powders. Powder Technol. 2003, 135-136, 50-58. 

Chan HK, Chew NYK. Excipients-powder and solid dosage forms. In Swarbrick J, Boylan JC, eds. Encyclopedia of Pharmaceutical Technology, 2nd edn, vol. 2. New York Marcel Dekker, 2002 1132-1142. 

S. Jonat, S. Hasenzahl, M. Drechsler, P. Albers, K.G. Wagner, P.C. Schmidt, Investigation of compacted hydrophilic and hydrophobic colloidal silicon dioxides as glidants for pharmaceutical excipients. Powder Technology, 141,31-43,2004. 

By foregoing use of the end cap, core sampler performance is improved further. In Figure 15-7 we display core sampling resnlts for three different inner-diameter sampling tubes using a two-layer bed of common pharmaceutical excipient powders microcrystalline cellulose and lactose. For aU sampler diameters, the experimental data are indistinguishable from ideal expected concentrations. In practice, we note that it is important that the walls of the sampling tubes be... 

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