Example The BHC Ibuprofen Process

In 1992, BASF opened a 35 000 tons per year ibuprofen production plant in Bishop, Texas. This plant was the result of the elegant green chemistry route developed by the BHC consortium. The clean synthesis of ibuprofen is an excellent example of how combining catalysis and green chemistry can yield both commercial success and environmental benefits. Ibuprofen is a nonsteroidal, anti-inflammatory painkiller. It is a popular over-the-counter drug against headache, toothache, and muscular pains. You may know it better as Advil , Motrin , or Nurofen. 

The BHC ibuprofen process is an innovative, efficient technology that has revolutionized bulk pharmaceutical manufacture. The process provides an elegant solution to a prevalent problem encountered in bulk pharmaceutical synthesis It avoids the large quantities of solvents and waste (especially aqueous salt waste 

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