Evoninoate alkaloids

MATA, R., CALZADA, F., DIAZ, E., TOSCANO, R.A., Chemical studies on Mexican plants used in traditional medicine. XV. Sesquiterpene evoninoate alkaloids from Hippocratea excelsa, J. Nat. Prod., 1990,53,1212-1219. 

The reddish brown bark, commonly known as cancerina of Hippocratea excelsa H.B.K., is valuable for treating skin ailments and gastric ulcers and for its pesticidal properties. The sesquiterpene evoninoate alkaloids hippocrateine I (58) and II (59), Fig. (18), were... 

A series of sesquiterpene evoninoate alkaloids have been isolated from the liana Hippocratea excelsa (Hippocrateaceae) from Mexico (Mata, 1993 Mata et al., 1990). This plant, called cancerina, is used medicinally to treat skin ailments and for its pesticidal properties. The main alkaloid, hippocrateine I (21), was cytotoxic in the 9 PS system (ED50 1.85 X 10 xg/ml) (Mata et al., 1990). This plant also contains small amounts of the antitumor triterpene tingenone (see Chapter 23). 

Mata, R., F. Calzada, E. Diaz, and R. A. Toscano, Sesquiterpene evoninoate alkaloids from Hippocratea excelsa, Planta Medica, 56, 517 (1990). 

TABLE IV. MACROCYCLIC ALKALOIDS FROM AMERICAN CELASTRACEAE (Evoninoate type)... 

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See also in sourсe #XX -- [ , ]

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